Drug Interactions & What to Avoid



There are so​me pharma meds that do not interact well with medicinal cannabis, for example morphine and cortisone. Each body is different however, and each person reacts differently; and this is why it is vitally important for any patient to monitor themselves whilst on treatment protocol and when they start weaning themselves off their pharma meds.




Warfarin: THC and CBD increase Warfarin levels (Yamaori et al 2012).  Frequent cannabis use has been associated with increased INR. Patients need to monitor INR closely, at least twice a week, as the cannabis will increase the levels – this means that the patient will have to decrease the Warfarin dosages.


Alcohol may increase THC levels (Hartman 2015).


Theophylline: Smoked cannabis can decrease Theophylline levels (Stout and Cimino 2014).


In children treated with CBD for epilepsy, CBD increased Clobazam.


Beta Blockers: Medicinal cannabis to be introduced gently and slowly.


Kidney problems: Medicinal cannabis to be introduced gently and slowly.


Methotrexate: Is a form of chemotherapy causing more harm than good.


Statins: We recommend patients come off them straight away if cholesterol is not chronic. They are toxic and one of the worst pharmaceuticals for the body.


Blood Pressure/Cholesterol: THC regulates BP and Cholesterol. Patients to closely monitor their levels and adjust meds accordingly.


Ritalin/Concerta: Takes 74 years to leave the body!


Steroids & Cortisone: Takes 6 months to get out of the body!


Cannabinoids do NOT like Morphine! Patient not to take FECO until weaned off Morphine.

Either stop and replace with a high cannabinoid dosage, or start low dosage and wean up to replace the morphine.


1.  Cannabinoid-Pharmaceutical Interactions

     Download PDF

2.  CBD Drug Interactions - What you need to know​

3.  www.drugs.com look up the pharmaceutical meds and where major interactions are

4.  www.webmd.com/drugs/2/index look up the pharmaceutical meds and where major interactions are

5.  Drug interactions (cannabis interactions)

6.  9 Prescription Medications You Should Avoid Mixing With Cannabis